- 专利标题： Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
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申请号： US13287900申请日： 2011-11-02
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公开(公告)号： US08975046B2公开(公告)日： 2015-03-10
- 发明人: Brian J. Brazeau , Mervyn L. De Souza , Steven J. Gort , Paula M. Hicks , Sherry R. Kollmann , Jose M. Laplaza , Sara C. McFarlan , Fernando A. Sanchez-Riera , Christopher Solheid
- 申请人： Brian J. Brazeau , Mervyn L. De Souza , Steven J. Gort , Paula M. Hicks , Sherry R. Kollmann , Jose M. Laplaza , Sara C. McFarlan , Fernando A. Sanchez-Riera , Christopher Solheid
- 申请人地址： US MN Wayzata
- 专利权人： Cargill, Incorporated
- 当前专利权人： Cargill, Incorporated
- 当前专利权人地址： US MN Wayzata
- 主分类号： C12P17/10
- IPC分类号： C12P17/10 ; C12P13/22 ; C12N9/10 ; C12N9/90
摘要：
Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
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