Intermediates for the preparation of analogs of halichondrin B

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US08975422B2 Intermediates for the preparation of analogs of halichondrin B 有权

Title translation: 用于制备软碱蛋白B类似物的中间体

Patent Title: Intermediates for the preparation of analogs of halichondrin B
Patent Title (中): 用于制备软碱蛋白B类似物的中间体
Application No.: US14250086

Application Date: 2014-04-10
Publication No.: US08975422B2

Publication Date: 2015-03-10
Inventor: Francis G. Fang , Bryan M. Lewis , Matthew Schnaderbeck
Applicant: Eisai R&D Management Co., Ltd.
Applicant Address: JP Tokyo
Assignee: Eisai R&D Management Co., Ltd.
Current Assignee: Eisai R&D Management Co., Ltd.
Current Assignee Address: JP Tokyo
Agency: Clark & Elbing LLP
Main IPC: C07D493/20
IPC: C07D493/20 ; C07D307/28 ; C07D307/33 ; C07D407/06 ; C07D407/14 ; C07D493/04 ; C07D493/08 ; C07D493/18 ; C07D493/22 ; C07D493/10 ; C07F7/18 ; C07D317/72 ; C07H15/26

Abstract:

Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.

Abstract(Chinese):

提供了中间体及其在合成类软绵母B合成中的应用方法。

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