Invention Grant
- Patent Title: Diphosphine ligand and transition metal complex using the same
- Patent Title (中): 二膦配体和过渡金属络合物使用它们
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Application No.: US14183827Application Date: 2014-02-19
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Publication No.: US08981147B2Publication Date: 2015-03-17
- Inventor: Mitsuhisa Yamano , Mitsutaka Goto , Shinji Kawaguchi , Masatoshi Yamada , Jun-ichi Kawakami
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-272599 20050920
- Main IPC: C07F9/50
- IPC: C07F9/50 ; C07F9/572 ; B01J31/24 ; C07B53/00 ; C07F15/00

Abstract:
The present invention provides a novel ligand represented by the following formula and a novel transition metal complex having the ligand, which shows superior enantioselectivity and catalytic efficiency, particularly high catalyst activity, in various asymmetric synthesis reactions.A transition metal complex having, as a ligand, a compound represented by the formula wherein R4 is a hydrogen atom or a C1-6 alkyl group optionally having substituent(s), and R5 and R6 are each a C1-6 alkyl group optionally having substituent(s), or the formula is a group represented by the formula wherein ring B is a 3- to 8-membered ring optionally having substituent(s).
Public/Granted literature
- US20140171655A1 DIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX USING THE SAME Public/Granted day:2014-06-19
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