Invention Grant
- Patent Title: Extravascular neuromodulation to treat heart failure
- Patent Title (中): 血管内神经调节治疗心力衰竭
-
Application No.: US13405909Application Date: 2012-02-27
-
Publication No.: US08983601B2Publication Date: 2015-03-17
- Inventor: Kiyotaka Fukamachi , Alex Massiello , Mariko Kobayashi , Ray Dessoffy , Eugene Jung , Shubhayu Basu
- Applicant: Kiyotaka Fukamachi , Alex Massiello , Mariko Kobayashi , Ray Dessoffy , Eugene Jung , Shubhayu Basu
- Applicant Address: US OH Cleveland
- Assignee: The Cleveland Clinic Foundation
- Current Assignee: The Cleveland Clinic Foundation
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: A61N1/00
- IPC: A61N1/00 ; A61N1/36 ; A61N1/362

Abstract:
Treatment of heart failure in a patient by electrically modulating both the sympathetic and parasympathetic autonomic cardiac nerve fibers that innervate the patient's heart at an extravascular site in the pericardial space of the heart. The extravascular site is any suitable single location inside the chest cavity that carries both sympathetic and parasympathetic cardiac nerves such as the cardiac plexus or the pericardial transverse sinus or any two separate extravascular sites with one site carrying predominantly sympathetic cardiac nerves and the other site carrying predominantly parasympathetic cardiac nerves for electrically modulating the balance of autonomic cardiac nerve control. Physiologic inputs from a neuromodulation system's own sensors or from separate implanted or external cardiovascular hemodynamic sensor systems can be used for closed loop control over the balance of sympathetic and parasympathetic cardiac autonomic effects on the patient's cardiac function in real time response to chronic and transient physiologic needs.
Public/Granted literature
- US20120221072A1 EXTRAVASCULAR NEUROMODULATION TO TREAT HEART FAILURE Public/Granted day:2012-08-30
Information query