According to one embodiment, there is provided an anti-vibration structure for a handle of a portable brush cutter, the structure including: a pole; an operation unit provided at a front portion of the pole; an engine provided and a lever device provided at a base portion of the pole; an attachment stay unit fixed to a middle portion of the pole, the attachment stay unit having an accommodation recess at each end thereof; an operation handle having a protrusion protruding from each end thereof; and anti-vibration materials sandwiched between the attachment stay unit and the handle main body in a left-right direction of the pole, so that one side of the anti-vibration material is accommodated in the accommodation recess while the protrusion is inserted in an open-groove formed on the other side of the anti-vibration material.