发明授权
- 专利标题: Morphinans useful as analgesics
- 专利标题(中): 吗啡可用作镇痛药
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申请号: US13981160申请日: 2011-12-23
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公开(公告)号: US08987293B2公开(公告)日: 2015-03-24
- 发明人: John Lawson
- 申请人: John Lawson
- 申请人地址: US UT Providence
- 专利权人: Phoenix Pharmalabs, Inc.
- 当前专利权人: Phoenix Pharmalabs, Inc.
- 当前专利权人地址: US UT Providence
- 代理机构: Cantor Colburn LLP
- 国际申请: PCT/US2011/067116 WO 20111223
- 国际公布: WO2012/088494 WO 20120628
- 主分类号: C07D221/28
- IPC分类号: C07D221/28 ; C07D221/22
摘要:
Compounds of Formula (I) are disclosed. The variables R1-R11 are described herein. Certain compounds of Formula (I) are partial agonists of the mu, delta, and kappa opioid receptors, and are useful for treating pain and opioid addiction, with fewer side effects than conventional opioids. Methods for preparing the disclosed compounds, pharmaceutical compositions containing compounds of Formula (I), and methods of treating pain and opioid addiction in patients are also disclosed.
公开/授权文献
- US20130338182A1 NOVEL MORPHINANS USEFUL AS ANALGESICS 公开/授权日:2013-12-19
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