发明授权
- 专利标题: Nanoscale bound bilayers, methods of use and production
- 专利标题(中): 纳米尺度双层膜,使用和生产方法
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申请号: US12865615申请日: 2009-01-30
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公开(公告)号: US08999320B2公开(公告)日: 2015-04-07
- 发明人: Thomas P. Sakmar , Thomas Huber , Sourabh Banerjee
- 申请人: Thomas P. Sakmar , Thomas Huber , Sourabh Banerjee
- 申请人地址: US NY New York
- 专利权人: The Rockefeller University
- 当前专利权人: The Rockefeller University
- 当前专利权人地址: US NY New York
- 代理机构: Thompson Coburn LLP
- 代理商 Charles P. Romano
- 国际申请: PCT/US2009/032745 WO 20090130
- 国际公布: WO2009/097587 WO 20090806
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K38/00 ; A61K47/00
摘要:
Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly obtaining a NABB not associated with membrane proteins. Immunogenic compositions comprising NABBs with native conformational epitopes are also provided along with their methods of use.
公开/授权文献
- US20110059159A1 NANOSCALE BOUND BILAYERS, METHODS OF USE AND PRODUCTION 公开/授权日:2011-03-10
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