发明授权
US09006283B2 Methods of modifying amyloid β oligomers using non-peptidic compounds
有权
淀粉样蛋白修饰方法 使用非肽化合物的低聚物
- 专利标题: Methods of modifying amyloid β oligomers using non-peptidic compounds
- 专利标题(中): 淀粉样蛋白修饰方法 使用非肽化合物的低聚物
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申请号: US11777264申请日: 2007-07-12
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公开(公告)号: US09006283B2公开(公告)日: 2015-04-14
- 发明人: Grant A. Krafft , Todd Pray , William F. Goure
- 申请人: Grant A. Krafft , Todd Pray , William F. Goure
- 申请人地址: US CA Livermore
- 专利权人: Acumen Pharmaceuticals, Inc.
- 当前专利权人: Acumen Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Livermore
- 代理机构: Foley & Lardner LLP
- 主分类号: A61K31/381
- IPC分类号: A61K31/381 ; A61K31/4155 ; A61K9/20 ; A61K9/00 ; A61K9/02 ; A61K9/14 ; A61K31/41 ; A61K31/415 ; C12N5/0793
摘要:
Disclosed are methods of inhibiting, regulating, and/or modulating the formation of soluble, globular, non-fibrillar, neurotoxic amyloid β1-42 oligomers from amyloid β1-42 monomers. Also disclosed are methods of treating a patient suffering from diseases associated with the formation of soluble, globular, non-fibrillar, neurotoxic amyloid β1-42 oligomers.
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