发明授权
- 专利标题： Crystalline polymorphic forms of an antidiabetic compound
- 专利标题（中）： 抗糖尿病化合物的结晶多晶型物
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申请号： US14186829申请日： 2014-02-21
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公开(公告)号： US09012488B2公开(公告)日： 2015-04-21
- 发明人: John Y. L. Chung , Yanfeng Zhang , Laura Artino , Aaron S. Cote , Donal Desmond , Jeremy Scott , Yekaterina Vaynshteyn
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Anna L. Cocuzzo; Catherine D. Fitch
- 主分类号： A61K31/405
- IPC分类号： A61K31/405 ; C07D209/12 ; C07D209/18
摘要：
The present invention relates to polymorphic forms of a compound of formula A: This compound is useful as a glucagon receptor antagonist and serves as a pharmaceutically active ingredient for the treatment of type 2 diabetes and related conditions, such as hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. Hydrates, hemihydrates, anhydrates and similar polymorphic forms are included.
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