Invention Grant
US09017644B2 Methods of treating autoimmune disorders and/or inflammatory disorders
有权
治疗自身免疫性疾病和/或炎症性疾病的方法
- Patent Title: Methods of treating autoimmune disorders and/or inflammatory disorders
- Patent Title (中): 治疗自身免疫性疾病和/或炎症性疾病的方法
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Application No.: US13126633Application Date: 2009-11-09
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Publication No.: US09017644B2Publication Date: 2015-04-28
- Inventor: James R. Baker, Jr. , Larry A. Sternson , David Repp , Deborah Ladenheim
- Applicant: James R. Baker, Jr. , Larry A. Sternson , David Repp , Deborah Ladenheim
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones S.C.
- International Application: PCT/US2009/063738 WO 20091109
- International Announcement: WO2010/054321 WO 20100514
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K49/12 ; A61K49/00 ; A61K49/08
Abstract:
The present invention relates to dendrimer compositions configured for treating inflammatory disorders and autoimmune disorders, and related methods of synthesis. Specifically, the present invention relates to methods for treating rheumatoid arthritis with PAMAM dendrimers having functional ligands configured for treating rheumatoid arthritis (e.g., therapeutic agents, pro-drugs, targeting agents, trigger agents, imaging agents) (e.g., methotrexate).
Public/Granted literature
- US20110268731A1 METHODS OF TREATING AUTOIMMUNE DISORDERS AND/OR INFLAMMATORY DISORDERS Public/Granted day:2011-11-03
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