Invention Grant
US09023869B2 Substituted phenylcarbamoyl alkylamino arene compounds and N,N'-BIS-arylurea compounds
有权
取代的苯基氨基甲酰基烷基氨基芳烃化合物和N，N'-BIS-芳基脲化合物
- Patent Title: Substituted phenylcarbamoyl alkylamino arene compounds and N,N'-BIS-arylurea compounds
- Patent Title (中): 取代的苯基氨基甲酰基烷基氨基芳烃化合物和N，N'-BIS-芳基脲化合物
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Application No.: US13685013Application Date: 2012-11-26
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Publication No.: US09023869B2Publication Date: 2015-05-05
- Inventor: Sarvajit Chakravarty , Rajendra Parasmal Jain
- Applicant: Sarvajit Chakravarty , Rajendra Parasmal Jain
- Applicant Address: US CA San Francisco
- Assignee: Medivation Technologies, Inc.
- Current Assignee: Medivation Technologies, Inc.
- Current Assignee Address: US CA San Francisco
- Agency: Banner & Witcoff, Ltd.
- Main IPC: C07C211/02
- IPC: C07C211/02 ; C07D207/04 ; A61K31/445 ; C07C237/30 ; C07D213/75 ; C07D213/81 ; C07D295/135 ; A61K31/277 ; A61K31/40 ; C07C255/50 ; C07D211/06
Abstract:
Substituted phenylcarbamoyl alkylamino arenes; substituted phenylthiocarbamyl alkylamino arenes; substituted phenylcarbamoyl alkylamino heteroarenes; substituted phenylthiocarbamyl alkylamino heteroarenes; N-substituted aryl, N′-substituted aryl urea compounds; N-substituted aryl, N′-substituted heteroaryl urea compounds; N-substituted aryl, N′-substituted aryl thiourea compounds and N-substituted aryl, N′-substituted heteroaryl thiourea compounds are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.
Public/Granted literature
- US20130079372A1 Substituted Phenylcarbamoyl Alkylamino Arene Compounds and N,N'-BIS-Arylurea Compounds Public/Granted day:2013-03-28
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