Disclosed herein is a method of generating an uplink reference signal in a system supporting a plurality of uplink access schemes. The method includes, at a base station, transmitting reference signal configuration information indicating the configuration of a reference signal to be transmitted in uplink, which is generated according to the plurality of uplink access schemes, to a user equipment which is set to operate in an uplink access scheme corresponding to the information, and receiving a subframe including the reference signal generated based on the reference signal configuration information from the user equipment. The reference signal configuration information includes a cyclic shift value of a sequence of the reference signal.