发明授权
US09034321B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases
有权
与苯丙氨酰-α-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
- 专利标题: Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases
- 专利标题(中): 与苯丙氨酰-α-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
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申请号: US13696046申请日: 2011-05-03
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公开(公告)号: US09034321B2公开(公告)日: 2015-05-19
- 发明人: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Jeffry D. Watkins , Cheryl L. Quinn , Wing-Sze Lo , John D. Mendlein
- 申请人: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Jeffry D. Watkins , Cheryl L. Quinn , Wing-Sze Lo , John D. Mendlein
- 申请人地址: US CA San Diego CN Hong Kong
- 专利权人: aTyr Pharma, Inc.,Pangu BioPharma Limited
- 当前专利权人: aTyr Pharma, Inc.,Pangu BioPharma Limited
- 当前专利权人地址: US CA San Diego CN Hong Kong
- 代理机构: Cooley LLP
- 国际申请: PCT/US2011/035053 WO 20110503
- 国际公布: WO2011/140132 WO 20111110
- 主分类号: A61K38/53
- IPC分类号: A61K38/53 ; A61K47/48 ; C07K16/40 ; C12N9/00 ; C12N5/071 ; C12N9/96 ; G01N33/68
摘要:
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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