A suture securement apparatus for selectively securing one or more ends of a suture while allowing adjustments in the tension or a full release of the sutures intermittently after a prolonged period of time. The suture securement apparatus can be particularly adapted for use with a purse-string suture to close a percutaneous catheter insertion site without causing puckering or distortion of the skin at the purse string suture site. The suture securement apparatus allows for subsequent modification of the amount of tensioning or full release of the sutures at the catheter insertion site. A threading assembly for use with the suture securement apparatus and being adapted to facilitate threading of sutures along the length of the suture securement apparatus. An adhesive suture securement device to provide securing sutures to be utilized with a suture securement apparatus. An adhesive securement device to provide a cradle configured to secure a hub of a catheter or other medical instrument or device.