发明授权
US09045499B2 Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
有权
杂芳基取代的六氢吡喃并[3,4-d] [1,3]噻嗪-2-胺化合物
![Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds](/docs/US/2015-06-02/US09045499B2/abs.jpg.600x600.jpg)
- 专利标题： Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
- 专利标题（中）： 杂芳基取代的六氢吡喃并[3,4-d] [1,3]噻嗪-2-胺化合物
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申请号： US14464935申请日： 2014-08-21
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公开(公告)号： US09045499B2公开(公告)日： 2015-06-02
- 发明人: Michael Aaron Brodney , Christopher Ryan Butler , Elizabeth Mary Beck , Jennifer Elizabeth Davoren , Erik Alphie LaChapelle , Brian Thomas O'Neill
- 申请人： Pfizer Inc.
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc.
- 当前专利权人： Pfizer Inc.
- 当前专利权人地址： US NY New York
- 代理商 John A. Wichtowski
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; A61K31/542
![Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds](/abs-image/US/2015/06/02/US09045499B2/abs.jpg.150x150.jpg)
摘要：
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1 and R2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
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