发明授权
US09045528B2 Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions 有权
具有在不同于互补决定区的分子区域中工程化的结合特性的合成免疫球蛋白结构域

Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
摘要:
A method of engineering immunoglobulins which each have one or more amino acid modifications in at least one structural loop region of such immunoglobulins, where the modified loop region specifically binds to an epitope of an antigen to which an unmodified immunoglobulin does not significantly bind.
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