Provided is a method and apparatus for controlling a user interface (UI) of an electronic device by using a specific region of a virtual plane. In the method, the virtual plane is initialized according to spatial coordinates of two or more images detected by using locations of the images displayed in an image display unit of a first image capture device and an image display unit of a second image capture device. Furthermore, the location of a marker is determined and is indicated by a specific image on the virtual plane. Furthermore, a screen pointer corresponding to the marker is displayed at a position where the marker is located in an image display unit corresponding to the virtual plane. Furthermore, a menu of the electronic device is selected which is pointed to by the screen pointer while moving the marker. Accordingly, a user can conveniently control the UI of the electronic device by performing a simple operation.