发明授权
- 专利标题： Substituted pyrimidinone-phenyl-pyrimidinyl compounds
- 专利标题（中）： 取代的嘧啶酮 - 苯基 - 嘧啶基化合物
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申请号： US13707326申请日： 2012-12-06
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公开(公告)号： US09056110B2公开(公告)日： 2015-06-16
- 发明人: Shaun R. Selness , Balekudru Devadas , Susan L. Hockerman , Joseph B. Monahan
- 申请人： Confluence Life Sciences, Inc.
- 申请人地址： US MO St. Louis
- 专利权人： CONFLUENCE LIFE SCIENCES, INC.
- 当前专利权人： CONFLUENCE LIFE SCIENCES, INC.
- 当前专利权人地址： US MO St. Louis
- 代理机构： Harness, Dickey & Pierce, P.L.C.
- 主分类号： A61K31/513
- IPC分类号： A61K31/513 ; A61K45/06 ; C07D401/14 ; C07D413/14 ; C07D409/14 ; C07D417/14 ; C07D403/14 ; C07D239/52
摘要：
The present disclosure provides pyrimidinone-phenyl-pyrimidinyl compounds useful in the treatment of p38 kinase mediated diseases, such as lymphoma and inflammatory disease, having the structure of Formula (I): wherein R1, R2, R3, R4 and R5 are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating p38 kinase mediated diseases using the compound.
公开/授权文献
- US20130143906A1 SUBSTITUTED PYRIMIDINONE-PHENYL-PYRIMIDINYL COMPOUNDS 公开/授权日：2013-06-06
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