Invention Grant
US09057056B2 Method for producing retrovirus using human producer cells with increased N-acetylglucosaminyltransferase III activity
有权
使用具有增加的N-乙酰葡糖胺基转移酶III活性的人生产细胞产生逆转录病毒的方法
- Patent Title: Method for producing retrovirus using human producer cells with increased N-acetylglucosaminyltransferase III activity
- Patent Title (中): 使用具有增加的N-乙酰葡糖胺基转移酶III活性的人生产细胞产生逆转录病毒的方法
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Application No.: US11663990Application Date: 2005-09-28
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Publication No.: US09057056B2Publication Date: 2015-06-16
- Inventor: Hideto Chono , Hiromi Okuyama , Tomoe Egashira , Nobuto Koyama , Junichi Mineno , Ikunoshin Kato
- Applicant: Hideto Chono , Hiromi Okuyama , Tomoe Egashira , Nobuto Koyama , Junichi Mineno , Ikunoshin Kato
- Applicant Address: JP Shiga
- Assignee: TAKARA BIO INC.
- Current Assignee: TAKARA BIO INC.
- Current Assignee Address: JP Shiga
- Agency: Browdy and Neimark, PLLC
- Priority: JP2004-283918 20040929
- International Application: PCT/JP2005/017875 WO 20050928
- International Announcement: WO2006/035829 WO 20060406
- Main IPC: C12N15/87
- IPC: C12N15/87 ; C12N15/63 ; C12N9/10 ; C12N15/86
Abstract:
The N-acetylglucosaminyltransferase III activity is enhanced in a cell carrying retrovirus-origin gag-pol gene and env gene. By constructing a retrovirus vector with the use of the above cell, a retrovirus vector having a modified sugar chain structure can be obtained. The retrovirus vector constructed by this method shows a high infection efficiency particularly in the presence of a functional substance.
Public/Granted literature
- US20080293141A1 Cell for Producing Retrovirus Vector Public/Granted day:2008-11-27
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