发明授权
- 专利标题: Gene expression technique
- 专利标题(中): 基因表达技术
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申请号: US11722539申请日: 2005-12-23
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公开(公告)号: US09057061B2公开(公告)日: 2015-06-16
- 发明人: Christopher John Arthur Finnis , Darrell Sleep , Gillian Shuttleworth
- 申请人: Christopher John Arthur Finnis , Darrell Sleep , Gillian Shuttleworth
- 申请人地址: DK Bagsvaerd
- 专利权人: NOVOZYMES BIOPHARMA DK A/S
- 当前专利权人: NOVOZYMES BIOPHARMA DK A/S
- 当前专利权人地址: DK Bagsvaerd
- 代理商 Michael W. Krenicky
- 优先权: GB0329681.1 20031223; GB0329722.3 20031223
- 国际申请: PCT/GB2005/005085 WO 20051223
- 国际公布: WO2006/067511 WO 20060629
- 主分类号: C12N15/63
- IPC分类号: C12N15/63 ; C12N15/67 ; C12N15/81 ; C12P21/00 ; C12N9/90 ; C07K14/395 ; C07K14/79
摘要:
The present invention provides a method for producing a desired protein (such as a desired heterologous protein) comprising: (a) providing a host cell comprising a first recombinant gene encoding a protein comprising the sequence of a first chaperone protein, a second recombinant gene encoding a protein comprising the sequence of a second chaperone protein and a third gene, such as a third recombinant gene, encoding a desired protein (such as a desired heterologous protein), wherein the first and second chaperones are different; and (b) culturing the host cell in a culture medium to obtain expression of the first, second and third genes.
公开/授权文献
- US20080193977A1 Gene Expression Technique 公开/授权日:2008-08-14
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