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US09062046B2 Substituted imidazoquinoline derivatives as kinase inhibitors 有权
取代的咪唑并喹啉衍生物作为激酶抑制剂

Substituted imidazoquinoline derivatives as kinase inhibitors
Abstract:
The present invention relates to substituted imidazo[4,5-c]quinoline derivatives, the compounds of formula (I), wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of formula (I), and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammatory diseases and angiogenesis related disorders.
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