Embodiments of the invention relate to programming, configuring, and integrating networked embedded devices with other applications. Particular embodiments include an architecture having an application model layer that integrates the networked embedded devices with business application systems, by allowing the devices to be expressed as part of a business application concept. In certain embodiments, an intermediate device programming layer provides a network-centric programming abstraction, relieving the programmer of the details of low-level, node-centric programming. Finally, a self-optimizing run-time system layer adapts to the specific conditions in the deployed network embedded devices, by optimizing e.g. communication patterns and resource consumption based upon input from the higher layer(s). Embodiments may facilitate integration of networked embedded devices with the back ends of business applications, and may provide a unified extensible programming framework simplifying development of applications for network embedded devices.