Invention Grant
US09068084B2 Silica nanoparticles doped with dye having negative charge and preparing method thereof
有权
掺杂有负电荷的染料的二氧化硅纳米粒子及其制备方法
- Patent Title: Silica nanoparticles doped with dye having negative charge and preparing method thereof
- Patent Title (中): 掺杂有负电荷的染料的二氧化硅纳米粒子及其制备方法
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Application No.: US13574171Application Date: 2010-02-11
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Publication No.: US09068084B2Publication Date: 2015-06-30
- Inventor: Wensheng Yang , Jinglun Liang , Jun Li
- Applicant: Wensheng Yang , Jinglun Liang , Jun Li
- Applicant Address: CN
- Assignee: Wuxi Zodolabs Biotech Co., Ltd.
- Current Assignee: Wuxi Zodolabs Biotech Co., Ltd.
- Current Assignee Address: CN
- Agent James E. Walton; Damon R. Hickman
- Priority: CN201010001649 20100119
- International Application: PCT/CN2010/070648 WO 20100211
- International Announcement: WO2011/088627 WO 20110728
- Main IPC: C09K11/06
- IPC: C09K11/06 ; C01B33/12 ; C09C3/10 ; C09C1/30 ; C09K11/02 ; C01B33/18 ; B82Y30/00

Abstract:
Provided are silica nanoparticles doped with dyes having a negative charge by using cationic polyelectrolyte as templet and preparing method thereof. The nanoparticles have a core-shell structure, inner core comprises cationic polyelectrolyte aggregates, in which fluorescent dye having a negative charge and SiO2 are doped, and optional additive having a negative charge, the shell is consisted of SiO2, wherein the sum of negative charge carried by the additives and the fluorescent dye is less than that of positive charge carried by the polyelectrolyte aggregates. The preparing method comprises the following steps: preparing complex solution of polyelectrolyte and fluorescent dye; prehydrolysis of organosilicon source; coating with organosilicon source. The method can be applied to dope silica with various fluorescent dyes having a negative charge. Various dyes can be doped at the same time, the doping amount, and particle diameter and shape of the product can be controlled by the method. The nanoparticles are spherical, the particle diameter thereof is uniform, and colloid formed therefrom is stable.
Public/Granted literature
- US20120292572A1 Silica Nanoparticles Doped with Dye Having Negative Charge and Preparing Method Thereof Public/Granted day:2012-11-22
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