发明授权
- 专利标题: Retinaldehyde in the treatment of obesity, diabetes and other conditions
- 专利标题(中): 视黄醛治疗肥胖,糖尿病等症状
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申请号: US12919716申请日: 2009-02-27
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公开(公告)号: US09078852B2公开(公告)日: 2015-07-14
- 发明人: Jorge Plutzky , Ouliana Ziouzenkova
- 申请人: Jorge Plutzky , Ouliana Ziouzenkova
- 申请人地址: US MA Boston
- 专利权人: The Brigham and Women's Hospital, Inc.
- 当前专利权人: The Brigham and Women's Hospital, Inc.
- 当前专利权人地址: US MA Boston
- 代理机构: Law Office of: Michael A. Sanzo, LLC
- 国际申请: PCT/US2009/001238 WO 20090227
- 国际公布: WO2009/110983 WO 20090911
- 主分类号: A61K31/11
- IPC分类号: A61K31/11 ; A61P3/10 ; A61P3/04 ; A61P35/00 ; A61P9/10
摘要:
The present invention is directed to methods of treating a patient for a disease or condition associated with adipogenesis or insulin resistance by administering a retinaldehyde compound to the patient or a compound that increases endogenous retinaldehyde levels by inhibiting the enzyme retinaldehyde dehydrogenase 1.
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