A process variable transmitter is used to measure a process variable, and, in doing so, dynamically changes the resolution of the A/D converter based upon the measured value of the analog input signal. This can be done by automatically adjusting the configurable resolution gain adjustment based on the value of the analog signal being measured, by normalizing the input signal being measured so that it is centered in an optimal resolution window of the A/D converter, or by adjusting a voltage reference provided to the A/D converter.