The present application discloses a dynamic sub-frame configuration method in the TDD system. The method includes: in the case that the uplink and downlink sub-frame configuration of a cell and the uplink and downlink sub-frame configuration of its neighboring cell are different in the configuration of a sub-frame, a part of resources on the sub-frame are made to be silent for the cell, and the resources on the sub-frame corresponding to the resources not silenced on the sub-frame for cell are made to be silent for the neighboring cell; or, a part of resources on the sub-frame are made to be silent for the neighboring cell, and the resources on the sub-frame corresponding to the resources not silenced on the sub-frame for the neighboring cell are made to be silent for the cell. The present application further provides a dynamic sub-frame configuration apparatus in the TDD system. Not only can the problem that inter-cell interference is introduced during sub-frame switching in the TDD system be solved, but also the normal uplink and downlink measurement can be guaranteed, without affecting ACK/NACK feedback and HARQ process, and meantime the frequency spectrum utilization ratio is increased.