- 专利标题： Compounds for the treatment of proliferative disorders
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申请号： US14053845申请日： 2013-10-15
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公开(公告)号： US09090603B2公开(公告)日： 2015-07-28
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人： Synta Pharmaceuticals Corporation
- 申请人地址： US MA Lexington
- 专利权人： SYNTA PHARMACEUTICALS CORPORATION
- 当前专利权人： SYNTA PHARMACEUTICALS CORPORATION
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Wei Song
- 主分类号： C07D261/08
- IPC分类号： C07D261/08 ; C07D413/14 ; A61K31/42 ; A61K31/426 ; A61K31/4439 ; A61K31/4709 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; C07D413/04 ; A61K31/4725 ; A61K31/675 ; A61K45/06 ; C07D413/10 ; C07F9/653
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US20140045795A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 公开/授权日：2014-02-13
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