发明授权
- 专利标题： Antibody targeting osteoclast-related protein Siglec-15
- 专利标题（中）： 抗体靶向破骨细胞相关蛋白Siglec-15
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申请号： US13457967申请日： 2012-04-27
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公开(公告)号： US09090692B2公开(公告)日： 2015-07-28
- 发明人: Yoshiharu Hiruma , Eisuke Tsuda
- 申请人： Yoshiharu Hiruma , Eisuke Tsuda
- 申请人地址： JP Tokyo
- 专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人地址： JP Tokyo
- 代理机构： Foley & Lardner LLP
- 优先权： JP2007-265420 20071011
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/395 ; C07K16/28 ; A61K31/593 ; A61K31/663 ; A61K45/06
摘要：
To provide a method of detecting abnormal bone metabolism by using a gene strongly expressed in an osteoclast; a method of screening a compound having a therapeutic and/or preventive effect on abnormal bone metabolism; and a pharmaceutical composition for treating and/or preventing abnormal bone metabolism. Provision of a method of detecting abnormal bone metabolism by using the expression of human Siglec-15 gene as an index; a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation; and the like.
公开/授权文献
- US20120251485A1 ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN SIGLEC-15 公开/授权日：2012-10-04
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