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US09095270B2 Detection, measurement, and imaging of cells such as cancer and other biologic substances using targeted nanoparticles and magnetic properties thereof 有权
使用靶向纳米颗粒及其磁性能，检测，测量和成像细胞如癌症和其他生物物质

  • 专利标题： Detection, measurement, and imaging of cells such as cancer and other biologic substances using targeted nanoparticles and magnetic properties thereof
  • 专利标题（中）： 使用靶向纳米颗粒及其磁性能，检测，测量和成像细胞如癌症和其他生物物质
  • 申请号： US13503674
    申请日： 2010-11-05
  • 公开(公告)号： US09095270B2
    公开(公告)日： 2015-08-04
  • 发明人: Edward R. Flynn
  • 申请人： Edward R. Flynn
  • 申请人地址： US NM Alburquerque
  • 专利权人： Senior Scientific LLC
  • 当前专利权人： Senior Scientific LLC
  • 当前专利权人地址： US NM Alburquerque
  • 代理商 V. Gerald Grafe
  • 国际申请： PCT/US2010/055729 WO 20101105
  • 国际公布： WO2011/057146 WO 20110512
  • 主分类号： A61B5/05
  • IPC分类号： A61B5/05 ;  A61B5/04 ;  A61B5/06 ;  A61B5/00 ;  G01R33/26 ;  A61B19/00
Detection, measurement, and imaging of cells such as cancer and other biologic substances using targeted nanoparticles and magnetic properties thereof
摘要：
The present invention provides methods and apparatuses for detecting, measuring, or locating cells or substances present in even very low concentrations in vivo in subjects, using targeted magnetic nanoparticles and special magnetic systems. The magnetic systems can comprise magnetizing subsystems and sensors subsystems, including as examples SQUID sensors and atomic magnetometers. The magnetic systems can detect, measure, or location particles bound by antibodies to cells or substances of predetermined types. Example magnetic systems are capable of detecting sub-nanogram amounts of these nanoparticles.
摘要（中）：

本发明提供了用于使用靶磁性纳米颗粒和特殊磁系统来检测，测量或定位体内甚至非常低的体内浓度的细胞或物质的方法和装置。 磁性系统可以包括磁化子系统和传感器子系统，包括例如SQUID传感器和原子磁强计。 磁性系统可以检测，测量或定位由细胞或预定类型的物质的抗体结合的颗粒。 示例磁系统能够检测亚纳米量的这些纳米颗粒。

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