发明授权
- 专利标题: Polysialic acid derivatives
- 专利标题(中): 聚唾液酸衍生物
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申请号: US13650048申请日: 2012-10-11
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公开(公告)号: US09102714B2公开(公告)日: 2015-08-11
- 发明人: Dale Howard Hreczuk-Hirst , Sanjay Jain , Peter Laing , Gregory Gregoriadis , Ioannis Papaioannou
- 申请人: Lipoxen Technologies Limited
- 申请人地址: GB
- 专利权人: Lipoxen Technologies Limited
- 当前专利权人: Lipoxen Technologies Limited
- 当前专利权人地址: GB
- 代理机构: One3 IP Management, P.C.
- 代理商 Dean G. Stathakis; Peter D. Weinstein
- 优先权: EP03254988 20030812; EP03255200 20030821
- 主分类号: C07K1/107
- IPC分类号: C07K1/107 ; C07K1/13 ; C08B37/00 ; C07K14/00 ; C07K1/00 ; A61K47/48
摘要:
A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.
公开/授权文献
- US20130144043A1 POLYSIALIC ACID DERIVATIVES 公开/授权日:2013-06-06