Invention Grant
US09107926B2 Mutant selectivity and combinations of a phosphoinositide 3-kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
有权
磷酸肌醇3-激酶抑制剂化合物的突变选择性和组合以及用于治疗癌症的化学治疗剂
- Patent Title: Mutant selectivity and combinations of a phosphoinositide 3-kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
- Patent Title (中): 磷酸肌醇3-激酶抑制剂化合物的突变选择性和组合以及用于治疗癌症的化学治疗剂
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Application No.: US13912281Application Date: 2013-06-07
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Publication No.: US09107926B2Publication Date: 2015-08-18
- Inventor: Marcia Belvin , Lori Friedman , Deepak Sampath , Jeffrey Wallin
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Genetech, Inc.
- Agent Alex Andrus
- Main IPC: C07D498/00
- IPC: C07D498/00 ; C07D513/00 ; A61K31/553 ; A61K39/395 ; A61K45/06 ; A61K31/138 ; A61K31/337 ; A61K31/357 ; A61K31/4196 ; A61K31/437 ; A61K31/4523 ; A61K31/513 ; A61K31/555 ; A61K31/565 ; A61K31/573 ; A61K31/7068 ; G01N33/50 ; C12Q1/68 ; C07K16/32
Abstract:
Methods and compositions are provided for treating hyperproliferative disorders in patients with a PI3K inhibitor, GDC-0032 as a single agent or in combination with chemotherapeutic agents.
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