发明授权
- 专利标题: Process for the manufacture of a precursor of vitamin B1
- 专利标题(中): 制造维生素B1前体的方法
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申请号: US11795957申请日: 2006-01-24
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公开(公告)号: US09108925B2公开(公告)日: 2015-08-18
- 发明人: Werner Bonrath , Jocelyn Fischesser , Lisa Giraudi , Reinhard Karge
- 申请人: Werner Bonrath , Jocelyn Fischesser , Lisa Giraudi , Reinhard Karge
- 申请人地址: NL Heerlen
- 专利权人: DSM IP ASSETS B.V.
- 当前专利权人: DSM IP ASSETS B.V.
- 当前专利权人地址: NL Heerlen
- 代理机构: Nixon & Vanderhye P.C.
- 优先权: EP05001859 20050128
- 国际申请: PCT/EP2006/000600 WO 20060124
- 国际公布: WO2006/079504 WO 20060803
- 主分类号: C07D239/42
- IPC分类号: C07D239/42 ; C07D239/50 ; C07D417/06
摘要:
The present invention relates to a novel process for the manufacture of Grewe-diamine comprising the following step: hydrolyzing a compound of formula (II), wherein R is hydrogen or straight- or branched chain C1-4 alkyl, with an aqueous alkali or alkaline-earth metal hydroxide solution, characterized in that the hydrolysis is carried out in the presence of an organic solvent.
公开/授权文献
- US20080242863A1 Process For the Manufacture of a Precursor of Vitamin B1 公开/授权日:2008-10-02
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