Invention Grant
- Patent Title: Quinoline derivatives as bromodomain inhibitors
- Patent Title (中): 喹啉衍生物作为溴结构域抑制剂
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Application No.: US14549848Application Date: 2014-11-21
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Publication No.: US09108953B2Publication Date: 2015-08-18
- Inventor: Kerim Babaoglu , Britton K. Corkey , Robert H. Jiang , David Sperandio , Hai Yang
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D413/14 ; C07D451/04

Abstract:
This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula I wherein R1, R2, R3, R4, R7, W, X, and Z are as described herein.
Public/Granted literature
- US20150148344A1 QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS Public/Granted day:2015-05-28
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