Invention Grant
- Patent Title: Substituted benzoazepines as toll-like receptor modulators
- Patent Title (中): 取代苯并吖庚因作为toll样受体调节剂
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Application No.: US14180939Application Date: 2014-02-14
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Publication No.: US09126940B2Publication Date: 2015-09-08
- Inventor: James Jeffry Howbert , Gregory Dietsch , Robert Hershberg , Laurence E. Burgess , Joseph P. Lyssikatos , Brad Newhouse , Hong-Woon Yang
- Applicant: VentiRx Pharmaceuticals, Inc. , Array BioPharma, Inc.
- Applicant Address: US WA Seattle US CO Boulder
- Assignee: VentiRx Pharmaceuticals, Inc.,Array Biopharma, Inc.
- Current Assignee: VentiRx Pharmaceuticals, Inc.,Array Biopharma, Inc.
- Current Assignee Address: US WA Seattle US CO Boulder
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/55 ; C07D223/16 ; C07D223/14 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D401/04 ; C07D405/04 ; C07D405/10
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
Public/Granted literature
- US20140234376A1 Substituted Benzoazepines as Toll-Like Receptor Modulators Public/Granted day:2014-08-21
Information query
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