发明授权
- 专利标题: Tetrahydropyrazolopyrimidine compounds
- 专利标题(中): 四氢吡唑并嘧啶化合物
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申请号: US13907202申请日: 2013-05-31
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公开(公告)号: US09126999B2公开(公告)日: 2015-09-08
- 发明人: Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
- 申请人: Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
- 申请人地址: JP Tokyo
- 专利权人: EISAI R&D MANAGEMENT CO., LTD.
- 当前专利权人: EISAI R&D MANAGEMENT CO., LTD.
- 当前专利权人地址: JP Tokyo
- 代理机构: Buchanan Ingersoll & Rooney PC
- 主分类号: A01N43/90
- IPC分类号: A01N43/90 ; A61K31/519 ; C07D487/00 ; C07D471/04 ; C07D487/04
摘要:
Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
公开/授权文献
- US20130324547A1 TETRAHYDROPYRAZOLOPYRIMIDINE COMPOUNDS 公开/授权日:2013-12-05