发明授权
- 专利标题： Anti-DLL3 antibody
- 专利标题（中）： 抗DLL3抗体
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申请号： US13575861申请日： 2011-01-28
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公开(公告)号： US09127071B2公开(公告)日： 2015-09-08
- 发明人: Kenji Yoshida , Hiroyuki Aburatani , Shumpei Ishikawa
- 申请人： Kenji Yoshida , Hiroyuki Aburatani , Shumpei Ishikawa
- 申请人地址： JP Tokyo JP Tokyo
- 专利权人： CHUGAI SEIYAKU KABUSHIKI KAISHA,THE UNIVERSITY OF TOKYO
- 当前专利权人： CHUGAI SEIYAKU KABUSHIKI KAISHA,THE UNIVERSITY OF TOKYO
- 当前专利权人地址： JP Tokyo JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JP2010-019391 20100129
- 国际申请： PCT/JP2011/000485 WO 20110128
- 国际公布： WO2011/093097 WO 20110804
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/30 ; C12Q1/68 ; G01N33/574 ; A61K39/00
摘要：
It is intended to disclose an antibody which binds to DLL3 protein. Preferably, the antibody of the present invention recognizes a region from amino acids 216 to 492 in human DLL3 having the amino acid sequence as set forth in SEQ ID NO: 1. The present invention also provides a pharmaceutical composition, for example, an anticancer agent, comprising the antibody of the present invention as an active ingredient. The present invention further discloses a method for diagnosing cancer using the antibody of the present invention and a diagnostic drug for cancer comprising the antibody of the present invention.
公开/授权文献
- US20120328624A1 ANTI-DLL3 ANTIBODY 公开/授权日：2012-12-27
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