Invention Grant
- Patent Title: Anti-DLL3 antibody
- Patent Title (中): 抗DLL3抗体
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Application No.: US13575861Application Date: 2011-01-28
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Publication No.: US09127071B2Publication Date: 2015-09-08
- Inventor: Kenji Yoshida , Hiroyuki Aburatani , Shumpei Ishikawa
- Applicant: Kenji Yoshida , Hiroyuki Aburatani , Shumpei Ishikawa
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA,THE UNIVERSITY OF TOKYO
- Current Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA,THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2010-019391 20100129
- International Application: PCT/JP2011/000485 WO 20110128
- International Announcement: WO2011/093097 WO 20110804
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; C12Q1/68 ; G01N33/574 ; A61K39/00
Abstract:
It is intended to disclose an antibody which binds to DLL3 protein. Preferably, the antibody of the present invention recognizes a region from amino acids 216 to 492 in human DLL3 having the amino acid sequence as set forth in SEQ ID NO: 1. The present invention also provides a pharmaceutical composition, for example, an anticancer agent, comprising the antibody of the present invention as an active ingredient. The present invention further discloses a method for diagnosing cancer using the antibody of the present invention and a diagnostic drug for cancer comprising the antibody of the present invention.
Public/Granted literature
- US20120328624A1 ANTI-DLL3 ANTIBODY Public/Granted day:2012-12-27
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