Invention Grant
US09127275B2 Compositions and methods for inhibiting expression of klf-1 and bcl11a genes
有权
用于抑制klf-1和bcl11a基因表达的组合物和方法
- Patent Title: Compositions and methods for inhibiting expression of klf-1 and bcl11a genes
- Patent Title (中): 用于抑制klf-1和bcl11a基因表达的组合物和方法
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Application No.: US13992669Application Date: 2011-12-09
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Publication No.: US09127275B2Publication Date: 2015-09-08
- Inventor: Tatiana Novobrantseva , Brian Bettencourt , Stuart Milstein , Anna Borodovsky
- Applicant: Tatiana Novobrantseva , Brian Bettencourt , Stuart Milstein , Anna Borodovsky
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi, LLP
- International Application: PCT/US2011/064275 WO 20111209
- International Announcement: WO2012/079046 WO 20120614
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the KLF1 gene and the BCL11A gene, and methods of using such dsRNA compositions to inhibit expression of KLF1 and BCL11 A, respectively.
Public/Granted literature
- US20140018410A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF KLF-1 AND BCL11A GENES Public/Granted day:2014-01-16
Information query
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