发明授权
- 专利标题： Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
- 专利标题（中）： 将水溶性或水不溶性治疗剂局部输送到体腔表面
-
申请号： US14254160申请日： 2014-04-16
-
公开(公告)号： US09132211B2公开(公告)日： 2015-09-15
- 发明人: Eugene T. Michal , Matthew J. Pollman
- 申请人： COVIDIEN LP
- 申请人地址： US CO Colorado Springs
- 专利权人： The Spectranetics Corporation
- 当前专利权人： The Spectranetics Corporation
- 当前专利权人地址： US CO Colorado Springs
- 代理机构： Carter DeLuca Farrell & Schmidt LLP
- 主分类号： A61L29/08
- IPC分类号： A61L29/08 ; A61L29/16 ; A61L33/00 ; A61L29/14 ; A61M25/10
摘要：
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.