Invention Grant
- Patent Title: Method for screening a drug in retinal tissue
- Patent Title (中): 筛选视网膜组织中药物的方法
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Application No.: US14306898Application Date: 2014-06-17
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Publication No.: US09134300B2Publication Date: 2015-09-15
- Inventor: Ioannis Danias , Hyungsik Lim
- Applicant: Research Foundation of the City University of New York
- Applicant Address: US NY New York US NY Albany
- Assignee: Research Foundation of the City University of New York,Research Foundation of the State University of New York
- Current Assignee: Research Foundation of the City University of New York,Research Foundation of the State University of New York
- Current Assignee Address: US NY New York US NY Albany
- Agency: Schmeiser, Olsen & Watts, LLP
- Agent Peter J. Mikesell
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01J9/00 ; G01J4/00 ; G01N33/483 ; G01N21/63 ; G01N21/17 ; G01N21/21 ; A61B5/00 ; A61B3/10 ; G02B21/00
Abstract:
The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.
Public/Granted literature
- US20140295481A1 METHOD FOR SCREENING A DRUG IN RETINAL TISSUE Public/Granted day:2014-10-02
Information query
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