Invention Grant
- Patent Title: Heteroaromatic compounds and their use as dopamine D1 ligands
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Application No.: US14638608Application Date: 2015-03-04
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Publication No.: US09139561B2Publication Date: 2015-09-22
- Inventor: Michael Aaron Brodney , Jennifer Elizabeth Davoren , Amy Beth Dounay , Ivan Viktorovich Efremov , David Lawrence Firman Gray , Michael Eric Green , Jaclyn Louise Henderson , Chewah Lee , Scot Richard Mente , Steven Victor O'Neil , Bruce Nelsen Rogers , Lei Zhang
- Applicant: PFIZER INC.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Feng Shao
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D403/12 ; A61K31/506 ; A61K31/444 ; A61P25/18

Abstract:
The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), age-related cognitive decline, dementia, and Parkinson's disease.
Public/Granted literature
- US20150175573A1 HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS Public/Granted day:2015-06-25
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