In an apparatus and method for controlling an interface, a user interface (UI) may be controlled using information on a hand motion and a gaze of a user without separate tools such as a mouse and a keyboard. That is, the UI control method provides more intuitive, immersive, and united control of the UI. Since a region of interest (ROI) sensing the hand motion of the user is calculated using a UI object that is controlled based on the hand motion within the ROI, the user may control the UI object in the same method and feel regardless of a distance from the user to a sensor. In addition, since positions and directions of view points are adjusted based on a position and direction of the gaze, a binocular 2D/3D image based on motion parallax may be provided.