Techniques for segmentation of three-dimensional (3D) point clouds are described herein. An example of a method for user-assisted segmentation of a 3D point cloud described herein includes obtaining a 3D point cloud of a scene containing a target object; receiving a seed input indicative of a location of the target object within the scene; and generating a segmented point cloud corresponding to the target object by pruning the 3D point cloud based on the seed input.