发明授权
- 专利标题： Diazole amides
- 专利标题（中）： 二唑酰胺
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申请号： US14137479申请日： 2013-12-20
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公开(公告)号： US09169248B2公开(公告)日： 2015-10-27
- 发明人: Xi Chen , Dean R. Dragoli , Pingchen Fan , Juan C. Jaen , Yandong Li , Jay P. Powers , Viengkham Malathong , Sreenivas Punna , Hiroko Tanaka , Penglie Zhang
- 申请人： ChemoCentryx, Inc.
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 代理商 William B. Kezer
- 主分类号： C07D231/40
- IPC分类号： C07D231/40 ; C07D233/88 ; A61K31/4192 ; A61K31/4178 ; C07D401/12 ; A61K31/4196 ; A61K31/4155 ; A61K31/437 ; C07D471/04 ; A61K45/06
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US20140179733A1 DIAZOLE AMIDES 公开/授权日：2014-06-26
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