A cruise control system of a vehicle comprises a target generator, a speed controller, and a distance controller. The speed controller and the distance controller are each coupled to the target generator. The target generator is configured for generating a dynamic speed target and a dynamic distance target through real-time assessment of information characterizing current operating condition characterizing information. The speed controller is configured for utilizing the dynamic speed target for issuing commands to cause the vehicle to be operated at a road speed that is adaptive to the current operating condition characterizing information. The distance controller is configured for utilizing the dynamic distance target for issuing commands to cause the vehicle to be operated such that a distance between the vehicle and a leading vehicle is adaptive to the current operating condition characterizing information.