A system and method for enabling a telephone number to be called in an anonymous manner by associating an identifier with the telephone number and providing for calling the number via the identifier. In one embodiment, the telephone call, including communication of the telephone number is performed using encryption. The identifier may be an email address or user identifier. Other users may call the telephone number via a website that operates as a virtual payphone, using software downloaded to a computer or other communication device, or by calling a voice portal, for example.