发明授权
- 专利标题: SSX-2 peptides presented by HLA class II molecules
- 专利标题(中): 由HLA II类分子呈递的SSX-2肽
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申请号: US13028953申请日: 2011-02-16
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公开(公告)号: US09200047B2公开(公告)日: 2015-12-01
- 发明人: Danila Valmori , Maha Ayyoub
- 申请人: Danila Valmori , Maha Ayyoub
- 申请人地址: US NY New York
- 专利权人: Ludwig Institute for Cancer Research, Ltd.
- 当前专利权人: Ludwig Institute for Cancer Research, Ltd.
- 当前专利权人地址: US NY New York
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/47
摘要:
The invention describes HLA class II binding peptides encoded by the SSX-2 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the SSX-2 gene.
公开/授权文献
- US20110144186A1 SSX-2 PEPTIDES PRESENTED BY HLA CLASS II MOLECULES 公开/授权日:2011-06-16
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