Invention Grant
US09206118B2 Sulfated psyllium derivative for reducing the risk of chronic human diseases and method for preparing the same
有权
用于降低慢性人类疾病风险的硫酸化车前子衍生物及其制备方法
- Patent Title: Sulfated psyllium derivative for reducing the risk of chronic human diseases and method for preparing the same
- Patent Title (中): 用于降低慢性人类疾病风险的硫酸化车前子衍生物及其制备方法
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Application No.: US12847747Application Date: 2010-07-30
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Publication No.: US09206118B2Publication Date: 2015-12-08
- Inventor: Liangli Yu , Wei Liu , Zhouhong Xie , Qin Wang , Boce Zhang
- Applicant: Liangli Yu , Wei Liu , Zhouhong Xie , Qin Wang , Boce Zhang
- Applicant Address: US MD College Park
- Assignee: University of Maryland, College Park
- Current Assignee: University of Maryland, College Park
- Current Assignee Address: US MD College Park
- Agency: Rosenberg, Klein & Lee
- Main IPC: A61K36/68
- IPC: A61K36/68 ; C07C303/00 ; C07C303/26 ; A23L1/30 ; C07C303/44
Abstract:
The invention is directed to a method for preparing sulfated psyllium derivatives for use to reduce the risk of chronic human diseases. The sulfation of psyllium was carried out with sulfur, trioxide, pyridine, dimethylformamide and chlorosulfonic acid in pyridine. Six total sulfated psyllium derivatives named SP1, SP2, SP3, SPR1, SPR2, and SPR3 were prepared and evaluated for their morphological and rheological properties, and bile acid-binding abilities. The invention offers a novel approach to obtaining sulfated psyllium derivatives for use in functional foods or supplemental and pharmaceutical products to increase health benefits.
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