Invention Grant
- Patent Title: IL4/IL13 binding repeat proteins and uses
- Patent Title (中): IL4 / IL13结合重复蛋白和用途
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Application No.: US14225821Application Date: 2014-03-26
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Publication No.: US09206244B2Publication Date: 2015-12-08
- Inventor: Michael Baumann , Gaby Tresch , Steven Jacobs , Karyn O'Neil
- Applicant: Janssen Biotech, Inc.
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Eric Dichter
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K14/47 ; A61K38/00
Abstract:
IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.
Public/Granted literature
- US20140206599A1 IL4/IL13 Binding Repeat Proteins and Uses Public/Granted day:2014-07-24
Information query
