A two-dimension (2D) and three-dimension (3D) switchable display device and display driving method thereof are provided. Each pixel unit of the 2D and 3D switchable display device includes a first sub-pixel, a second sub-pixel and a third sub-pixel. The first sub-pixel, driven by a first gate line, has a first sub-pixel voltage, and the third sub-pixel, driven by a second gate line, has a third sub-pixel voltage different from the first sub-pixel voltage. The charge of the second sub-pixel is shared by a first gate line of an adjacent pixel unit, and the second sub-pixel has a second sub-pixel voltage different from the first sub-pixel voltage and the third sub-pixel voltage. The first sub-pixel, the second sub-pixel and the third sub-pixel of the pixel unit can be driven in a pre-charge driving manner.